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DOI 10.4103/jpbs.jpbs_1334_24

Медицинская библиотека · Journal of pharmacy & bioallied sciences · 2025

Anti-Caries Activity of New Generation Rechargeable Dental Composites - An In Vitro Study.

Savita Anjali, Verma Yashvi, Dubey Vertika, Dubey Priyanka, Najam Ayesha, Luhana Rinkal

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Аннотация

INTRODUCTION

Secondary caries at the restorative margins is the common reason for dental composite restoration failure. Our objectives were to evaluate the anti-caries activity of new generation rechargeable composites and to evaluate three different concentrations of quaternary ammonium methacrylate compound on S. mutans biofilm.

MATERIAL AND

METHODS

The composite resin consisted of urethane dimethacrylate and triethylene glycol divinylbenzyl ether and was prepared with 2%, 5%, and 8% of dimethylaminohexadecyl methacrylate (DMAHDM) and 20% of nanoparticles of amorphous calcium phosphate for remineralization.

RESULT: It was found that the incorporation of 8% DMAHDM significantly reduced S. mutans biofilm colony-forming units by 2-5 log by 7 folds, compared to the composite with 2% DMAHDM (P < 0.05) and nonsignificantly to 5% group. Adding 5% DMAHDM provides sustained Ca and P ion release as compared to 2% and 8% groups.

CONCUSION: Hence, it was concluded that the composite with DMAHDM content increased the antibacterial effect in a dose-dependent manner and provided sustained Ca and P ion release till 70 days.

Для цитирования: Savita Anjali, Verma Yashvi, Dubey Vertika, Dubey Priyanka, Najam Ayesha, Luhana Rinkal. Anti-Caries Activity of New Generation Rechargeable Dental Composites - An In Vitro Study.. Journal of pharmacy & bioallied sciences. 2025. DOI: 10.4103/jpbs.jpbs_1334_24.
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