Life event stress in duodenal ulcer compared with functional dyspepsia: a case-control study.

This is a prospective study of life event stress in 80 duodenal ulcer patients compared with 80 patients with functional dyspepsia and 80 healthy controls; matched for age, sex and marital status. A semi structured psychiatric interview was used in the psychiatric assessment of the dyspeptic patients and controls. A modified version of Life Events Scale by Tennant and Andrews was used in the assessment of life event stress. More dyspeptic patients reported life events than the controls, but, on the whole, the differences were not statistically significant. On the other hand, more patients with functional dyspepsia experienced life events than the patients with duodenal ulcer, but again the results were not consistent. Life event stress as measured by the experience of undesirable life events was significantly reported by more patients with functional dyspepsia. The significance of the presence of life events in duodenal ulcer and functional dyspepsia patients is not substantiated in the present study, as the positive findings were few and sometimes inconsistent. More quantitative studies are needed, taking into consideration the other aspects of the problem like personality, cognition and the complex interaction of stressors and personality.