Tuberculous and brucellosis meningitis differential diagnosis.
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Erdem Hakan, Senbayrak Seniha, Gencer Serap, Hasbun Rodrigo, Karahocagil Mustafa Kasim, Sengoz Gonul, Karsen Hasan, Kaya Selçuk, Civljak Rok, Inal Ayşe Seza, Pekok Abdullah Umut, Celen Mustafa Kemal, Deniz Secil, Ulug Mehmet, Demirdal Tuna, Namiduru Mustafa, Tekin Recep, Guven Tumer, Parlak Emine, Bolukcu Sibel, Avci Meltem, Sipahi Oğuz Reşat, Nayman-Alpat Saygin, Yaşar Kadriye, Pehlivanoğlu Filiz, Yilmaz Emel, Ates-Guler Selma, Mutlu-Yilmaz Esmeray, Tosun Selma, Sirmatel Fatma, Şahin-Horasan Elif, Akbulut Ayhan, Johansen Işik Somuncu, Simeon Soline, Batirel Ayşe, Öztoprak Nefise, Cag Yasemin, Catroux Melanie, Hansmann Yves, Kadanali Ayten, Turgut Huseyin, Baran Ali Irfan, Gul Hanefi Cem, Karaahmetoglu Gokhan, Sunnetcioglu Mahmut, Haykir-Solay Asli, Denk Affan, Ayaz Celal, Kose Sukran, Gorenek Levent
Аннотация
METHOD: BME and TBM patients from 35 tertiary hospitals were included in this study. Overall 294 adult patients with BME and 190 patients with TBM were enrolled. All patients involved in the study had microbiological confirmation for either TBM or BME. Finally, the Thwaites and Lancet scoring systems were assessed in both groups.
RESULTS: The Thwaites scoring system more frequently predicted BME cases (n = 292, 99.3%) compared to the TBM group (n = 182, 95.8%) (P = 0.017). According to the Lancet scoring system, the mean scores for BME and TBM were 9.43 ± 1.71 and 11.45 ± 3.01, respectively (P < 0.001). In addition, TBM cases were classified into "probable" category more significantly compared to BME cases, and BME cases were categorized into the "possible" category more frequently.
CONCLUSIONS: When the Thwaites or Lancet scoring systems indicate TBM, brucellar etiology should also be taken into consideration particularly in endemic countries.