Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials · 2010
[Dynamic study on inhibition of qi-benefiting, blood-activating recipe on myocardial hypertrophy induced by ISO in rats].
Аннотация на английскомСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Lv Rong, Zhang Chen, Liu Yan, Gu Yan-pin, Huang Wei, Guo Wei, Wei Hong-chang, Chen Li-yun
Аннотация
OBJECTIVE: To observe the effect of Qi-Benefiting, Blood-Activating Recipe on the different pathologic stage of myocardial hypertrophy induced by ISO in rats.
METHODS: Myocardial hypertrophy rats were induced by isoproterenol, and treated with Qi-Benefiting, Blood-Activating Recipe for 5,10 and 15 weeks, hemodynamic parameters, LVMI, HMI were determined, ANP and BNP were analysed.
RESULTS: Qi-Benefiting, Blood-Activating Recipe could increase cardiac output and improve hemodynamic parameters all after 5, 10 and 15 weeks' treatment (P<0.05). It could decrease the contents of ANP and BNP after 5, 10 and 15 weeks' treatment (P<0.05). Qi-Benefiting, Blood-Activating Recipe could significantly decrease the levels of HWI and LVMI after 5, 10 and 15 weeks' treatment (P<0.05).
CONCLUSION: Qi-Benefiting, Blood-Activating Recipe can significant improve hemodynamic status, increase cardiac output and decrease the level of neurohormonal factors.
METHODS: Myocardial hypertrophy rats were induced by isoproterenol, and treated with Qi-Benefiting, Blood-Activating Recipe for 5,10 and 15 weeks, hemodynamic parameters, LVMI, HMI were determined, ANP and BNP were analysed.
RESULTS: Qi-Benefiting, Blood-Activating Recipe could increase cardiac output and improve hemodynamic parameters all after 5, 10 and 15 weeks' treatment (P<0.05). It could decrease the contents of ANP and BNP after 5, 10 and 15 weeks' treatment (P<0.05). Qi-Benefiting, Blood-Activating Recipe could significantly decrease the levels of HWI and LVMI after 5, 10 and 15 weeks' treatment (P<0.05).
CONCLUSION: Qi-Benefiting, Blood-Activating Recipe can significant improve hemodynamic status, increase cardiac output and decrease the level of neurohormonal factors.