Annales d'endocrinologie · 2009
[Update of oral vitamin B12].
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Andres E, Serraj K, Mecili M, Ciobanu E, Vogel T, Weitten T
Аннотация
OBJECTIVE: The objective of this review is to evaluate the usefulness of oral cobalamin (vitamin B12) treatment.
MATERIAL AND METHOD: PubMed was systematically searched for English and French articles published from January 1990 to January 2007.
RESULTS: Prospective randomized studies (n = 3), a systematic review by the Cochrane group (n = 1) and prospective studies in well-determined population (n = 5) provide evidence that oral cyanocobalamin therapy may adequately treat cobalamin deficiency in elderly patients. However, the current literature may not suggest a strategy in terms of the form (hydroxy- or cyanocobalamin), frequency and duration of the treatment.
CONCLUSION: This present review confirms the previously reported efficacy of oral cyanocobalamin treatment in elderly patients.
MATERIAL AND METHOD: PubMed was systematically searched for English and French articles published from January 1990 to January 2007.
RESULTS: Prospective randomized studies (n = 3), a systematic review by the Cochrane group (n = 1) and prospective studies in well-determined population (n = 5) provide evidence that oral cyanocobalamin therapy may adequately treat cobalamin deficiency in elderly patients. However, the current literature may not suggest a strategy in terms of the form (hydroxy- or cyanocobalamin), frequency and duration of the treatment.
CONCLUSION: This present review confirms the previously reported efficacy of oral cyanocobalamin treatment in elderly patients.