Problemy endokrinologii · 2024
KI-67 as a predictive indicator of papillary thyroid cancer in Iraqi patients.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Al-Timimi Noor Mohammed, Baraaj Abed Hassan
Аннотация
BACKGROUND: KI-67 (MKI-67 in humans) is a protein able to bind to DNA which contributes to cell growth and cell proliferation. KI-67 is currently considered as a biomarker that is widely utilized as prognostic indicator for evaluating cell proliferation, diagnosing diseases, and conducting research. Several different kinds of cancer have high Ki-67 expression, which simplifying the choice of treatment for individuals with various cancer types.
AIM: The objective was to evaluate the expression of KI67 in patients suffering papillary thyroid cancer (PTC) also the association between patients age and gender and KI67 expression.
MATERIALS AND METHODS: To undertake an in-depth investigation of KI67 in malignant and normal tissues, we used thyroid tissue sections to analyze KI67 expression in 70 samples, 50 different PTC (44 female and 6 male), and 20 normal types (10 for each gender). Each group's average age is between 20 and 60.
RESULTS: The analysis of the data revealed a substantial difference in the expression of ki67 between the patients and control groups. Ki67 expression and either gender or age did not significantly correlate.
CONCLUSION: This study suggest that KI67 may be a crucial marker for assessing the aggressiveness of tumors and inflammatory diseases.
AIM: The objective was to evaluate the expression of KI67 in patients suffering papillary thyroid cancer (PTC) also the association between patients age and gender and KI67 expression.
MATERIALS AND METHODS: To undertake an in-depth investigation of KI67 in malignant and normal tissues, we used thyroid tissue sections to analyze KI67 expression in 70 samples, 50 different PTC (44 female and 6 male), and 20 normal types (10 for each gender). Each group's average age is between 20 and 60.
RESULTS: The analysis of the data revealed a substantial difference in the expression of ki67 between the patients and control groups. Ki67 expression and either gender or age did not significantly correlate.
CONCLUSION: This study suggest that KI67 may be a crucial marker for assessing the aggressiveness of tumors and inflammatory diseases.