Clinical journal of gastroenterology · 2021
A case of focal nodular hyperplasia with hepatic failure treated with liver transplantation.
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Yasunaka Tetsuya, Takeuchi Yasuto, Takaki Akinobu, Kondo Fukuo, Yoshizumi Tomoharu, Kohashi Kenichi, Oyama Atsushi, Adachi Takuya, Wada Nozomu, Onishi Hideki, Shiraha Hidenori, Okada Hiroyuki
Аннотация
Focal nodular hyperplasia (FNH) is a benign nodular lesion, but because of its feature of portal tract vessel abnormality, it may induce portal hypertension. A 27-year-old woman was admitted with a fever. A large nodule with satellite lesions was found in the liver and cotton wool-like feature of arteries were detected on angiography. Technetium galactosyl serum albumin scintigraphy and diagnostic laparoscopy showed that the tumor site was functional, while the surrounding area was a non-functional fibrotic area. A biopsy specimen indicated that the nodular lesion was an FNH-like lesion. She experienced several instances of variceal rupture and suffered liver failure, receiving liver transplantation. The excised liver showed a centrally scarred area in the nodule, indicating that the diagnosis was FNH. We herein report this case as a rare case of FNH that progressed to liver failure.