Clinical Research on the Aortic Elasticity in Patients with Type 1 Diabetes Mellitus Complicated with Hypertension.

OBJECTIVE

To investigate the characteristics of aortic elasticity in type 1 diabetes mellitus (DM1) patients with hypertension using dual-source computed tomography (DSCT).

METHODS

Subjects were divided into four groups: 31 with hypertension (EH group), 28 with DM1 (DM1 group), 30 with hypertension and DM1 (DM1 + EH group), and 30 healthy volunteers (control group, CG). ECG-gated DSCT was used to measure the cross-sectional area of the aorta in diastole and systole and calculate the aortic elasticity (D). Analysis of variance and multiple linear regression were used for statistical analysis.

RESULTS

Compared with the CG, aortic elasticity (D) in the DM1 group patients was not significantly decreased. Compared with the EH group, the DM1 + EH group showed no significant change. The aortic elasticity (D) in the EH and DM1 + EH groups was significantly lower than that in the CG and DM1 group.

CONCLUSION

DM1 slightly affects the aortic elasticity of the descending aorta, whereas hypertension exerts the main effect.