[Analysis of the correlation between olfactory dysfunction in chronic rhinosinusitis and change in nasal cavity structure based on multimodal magnetic resonance].

Objective:Use Multimodal Magnetic Resonance Imaging（MM-MRI） to analyze the correlation between olfactory dysfunction（OD） in patients with Chronic Rhinosinusitis（CRS） and the changes in nasal cavity structure. Methods: A retrospective analysis was conducted on 67 patients with chronic rhinosinusitis （CRS） treated at our hospital between January 2022 and December 2024 Based on olfactory function assessment, patients were divided into the observation group（with olfactory dysfunction, n=51） and the control group（without olfactory dysfunction, n=16）. The scores of the Chinese Sniff Identification Test（CSIT）, the width of the olfactory cleft（a nasal cavity structure） and the volume of the olfactory bulb（an olfactory nerve-related structure） were compared between the two groups, Additionally, correlations between these parameters and olfactory dysfunction were analyzed. Results:The CSIT scores of the patients in the observation group were significantly lower than those in the control group. Compared to the control group, the observation group exhibited reduced olfactory cleft width and smaller olfactory bulb volume （P<0.05）. Pearson analysis revealed a certain association between olfactory function and both olfactory cleft width and olfactory bulb volume. Conclusion:Olfactory dysfunction in CRS patients is significantly correlated with olfactory cleft width and olfactory bulb volume. Olfactory cleft width and olfactory bulb volume can serve as potential indicators for evaluating the degree of OD in CRS patients, but their causal relationship with OD requires further research and verification.