Ocular immunology and inflammation · 2009
Bilateral anterior granulomatous keratouveitis with sunset glow fundus in a patient with autoimmune polyglandular syndrome.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Futagami Yuri, Sugita Sunao, Fujimaki Takuro, Yokoyama Toshiyuki, Morio Tomohiro, Mochizuki Manabu
Аннотация
AIM: To report the case of a patient with bilateral anterior granulomatous keratouveitis and sunset glow fundus.
METHOD: Review of case record.
RESULTS: A 15-year-old patient had bilateral anterior granulomatous keratouveitis and sunset glow fundus similar to findings in Vogt-Koyanagi-Harada disease (VKH). However, the patient also suffered additional autoimmune disease against endocrine glands. In addition to anti-thyroid antibody and anti-glutamic acid decarboxylase antibody, anti-melanocyte autoantibody was detected in serum from this patient. The authors finally diagnosed autoimmune polyglandular syndrome.
CONCLUSION: If resistance against treatment exists for VKH, particularly in pediatric cases, this disease should be considered and other endocrine disorders examined.
METHOD: Review of case record.
RESULTS: A 15-year-old patient had bilateral anterior granulomatous keratouveitis and sunset glow fundus similar to findings in Vogt-Koyanagi-Harada disease (VKH). However, the patient also suffered additional autoimmune disease against endocrine glands. In addition to anti-thyroid antibody and anti-glutamic acid decarboxylase antibody, anti-melanocyte autoantibody was detected in serum from this patient. The authors finally diagnosed autoimmune polyglandular syndrome.
CONCLUSION: If resistance against treatment exists for VKH, particularly in pediatric cases, this disease should be considered and other endocrine disorders examined.