The Journal of laryngology and otology · 2026
Efficacy of stellate ganglion block for refractory sensorineural olfactory dysfunction: a systematic review and meta-analysis.
СтатьяСистематический обзорМетаанализНазвание и аннотация: Перевод в очереди
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Kim Do Hyun, Jang David W, Hwang Se Hwan
Аннотация
OBJECTIVE: To evaluate the efficacy and safety of stellate ganglion block for persistent and refractory sensorineural olfactory dysfunction.
METHODS: A systematic search of PubMed, Scopus, Embase, Web of Science, Google Scholar and the Cochrane Library was conducted for studies published before December 2025. Eligible studies assessed subjective and/or objective olfactory outcomes before and after stellate ganglion block and, when available, compared stellate ganglion block with placebo or no treatment.
RESULTS: Nine studies involving 441 participants were included. Stellate ganglion block was associated with greater improvements in olfactory composite, identification and subjective scores than controls, but between-group differences were not statistically significant. Subjective and objective improvement rates following stellate ganglion block were 68.9 and 63.4 per cent, respectively. No major adverse events were reported.
CONCLUSION: Stellate ganglion block appears safe and may provide modest olfactory improvement, but its superiority over control treatments remains unproven, warranting further randomised controlled trials.
METHODS: A systematic search of PubMed, Scopus, Embase, Web of Science, Google Scholar and the Cochrane Library was conducted for studies published before December 2025. Eligible studies assessed subjective and/or objective olfactory outcomes before and after stellate ganglion block and, when available, compared stellate ganglion block with placebo or no treatment.
RESULTS: Nine studies involving 441 participants were included. Stellate ganglion block was associated with greater improvements in olfactory composite, identification and subjective scores than controls, but between-group differences were not statistically significant. Subjective and objective improvement rates following stellate ganglion block were 68.9 and 63.4 per cent, respectively. No major adverse events were reported.
CONCLUSION: Stellate ganglion block appears safe and may provide modest olfactory improvement, but its superiority over control treatments remains unproven, warranting further randomised controlled trials.