Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology · 2003
[Clinical significance of inflammatory reaction in patients with coronary heart disease].
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Wang Yong, Ding Ti-long, Zhang Ling-ling, Yan Jia-chun, Yu Xiao-zhong, Shi Jian
Аннотация
AIM: To explore the relationship between inflammatory reaction and coronary heart disease (CHD).
METHODS: 101 CHD patients were divided into 3 groups, namely 19 ca-ses of stable angina pectoris ( SAP) , 33 cases of unstable angina pectoris( UAP) and 49 cases of acute myocardial infarction( AMI). Control group C-reactive protein( CRP) level and sum of white blood cells ( WBC) in peripheral blood were detected by immunoturbidimetry and hemocytometer,respectively. Pathological changes in 20 AMI tissue slice were examined by histochemical staining.
RESULTS: The CRP level and sum of WBCs in UAP group were higher than those in SAP group ( P < 0. 05 ), but distinctly lower than those in AMI group (P<0.01). The CRP level and sum of WBCs in AMI group and UAP group were notably higher than those in normal control group (P <0. 01). Histochemical staining showed that there were a great number of leucocyte in-filtration in cardiac muscle of AMI patients.
CONCLUSION: The inflammatory reaction participants in genesis and development of CHD. CRP level and sum of WBCs may become a useful index for monitoring CHD patient's condition and prejudging the risk of suffering from CHD.
METHODS: 101 CHD patients were divided into 3 groups, namely 19 ca-ses of stable angina pectoris ( SAP) , 33 cases of unstable angina pectoris( UAP) and 49 cases of acute myocardial infarction( AMI). Control group C-reactive protein( CRP) level and sum of white blood cells ( WBC) in peripheral blood were detected by immunoturbidimetry and hemocytometer,respectively. Pathological changes in 20 AMI tissue slice were examined by histochemical staining.
RESULTS: The CRP level and sum of WBCs in UAP group were higher than those in SAP group ( P < 0. 05 ), but distinctly lower than those in AMI group (P<0.01). The CRP level and sum of WBCs in AMI group and UAP group were notably higher than those in normal control group (P <0. 01). Histochemical staining showed that there were a great number of leucocyte in-filtration in cardiac muscle of AMI patients.
CONCLUSION: The inflammatory reaction participants in genesis and development of CHD. CRP level and sum of WBCs may become a useful index for monitoring CHD patient's condition and prejudging the risk of suffering from CHD.