[Clinical significance of inflammatory reaction in patients with coronary heart disease].

AIM: To explore the relationship between inflammatory reaction and coronary heart disease (CHD).

METHODS

101 CHD patients were divided into 3 groups, namely 19 ca-ses of stable angina pectoris ( SAP) , 33 cases of unstable angina pectoris( UAP) and 49 cases of acute myocardial infarction( AMI). Control group C-reactive protein( CRP) level and sum of white blood cells ( WBC) in peripheral blood were detected by immunoturbidimetry and hemocytometer,respectively. Pathological changes in 20 AMI tissue slice were examined by histochemical staining.

RESULTS

The CRP level and sum of WBCs in UAP group were higher than those in SAP group ( P < 0. 05 ), but distinctly lower than those in AMI group (P<0.01). The CRP level and sum of WBCs in AMI group and UAP group were notably higher than those in normal control group (P <0. 01). Histochemical staining showed that there were a great number of leucocyte in-filtration in cardiac muscle of AMI patients.

CONCLUSION

The inflammatory reaction participants in genesis and development of CHD. CRP level and sum of WBCs may become a useful index for monitoring CHD patient's condition and prejudging the risk of suffering from CHD.