Head & neck · 2020
Risk factors for subsequent recurrence after surgical treatment of recurrent pleomorphic adenoma of the parotid gland.
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Rooker Steven A, Van Abel Kathryn M, Yin Linda X, Nagelschneider Alex A, Price Daniel L, Olsen Kerry D, Janus Jeffrey R, Kasperbauer Jan L, Moore Eric J
Аннотация
BACKGROUND: Recurrent pleomorphic adenoma (PA) can be a lifelong disease, and rates of subsequent recurrence are high.
METHODS: Patients between 2000 and 2015 were identified. Primary outcome was subsequent recurrence after surgical salvage.
RESULTS: Twenty-seven of 84 patients developed a subsequent recurrence. Risk factors for subsequent recurrence included a higher number of previous recurrences (P < .01), worse preoperative facial nerve function (P < .01), and deep parotid lesion(s) (P < .01). Interval since last surgery was protective (P < .01), specifically >10 years since last surgery (P < .01). For patients with a >10-year interval since their last surgery, the subsequent recurrence-free rate at 10 years follow-up was 80.2% vs 31.8%.
CONCLUSIONS: For patients presenting with a >10-year interval since their last surgery, subsequent recurrence rates are low, which may allow for as needed surveillance recommendations. For patients presenting with recurrent PA and ≤10 years since their last surgery, a closer surveillance is warranted.
METHODS: Patients between 2000 and 2015 were identified. Primary outcome was subsequent recurrence after surgical salvage.
RESULTS: Twenty-seven of 84 patients developed a subsequent recurrence. Risk factors for subsequent recurrence included a higher number of previous recurrences (P < .01), worse preoperative facial nerve function (P < .01), and deep parotid lesion(s) (P < .01). Interval since last surgery was protective (P < .01), specifically >10 years since last surgery (P < .01). For patients with a >10-year interval since their last surgery, the subsequent recurrence-free rate at 10 years follow-up was 80.2% vs 31.8%.
CONCLUSIONS: For patients presenting with a >10-year interval since their last surgery, subsequent recurrence rates are low, which may allow for as needed surveillance recommendations. For patients presenting with recurrent PA and ≤10 years since their last surgery, a closer surveillance is warranted.