International journal of urology : official journal of the Japanese Urological Association · 1997
Preoperative localization of parathyroid adenomas using 99mTc-MIBI scintigraphy in patients with hyperparathyroidism.
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Ebisuno S, Inagaki T, Yoshida T, Yamamoto M, Tabuse Y, Kohjimoto Y, Ohkawa T
Аннотация
BACKGROUND: Technetium (Tc)99m methoxyisobutyl isonitrile (99mTc-MIBI) has recently been introduced for parathyroid imaging, as well as for myocardial imaging. We studied the usefulness of 99mTc-MIBI scintigraphy for preoperative localization of abnormal parathyroid glands.
METHODS: The usefulness of 99mTc-MIBI scintigraphy for detection of hyperfunctional parathyroid lesions was evaluated in 5 patients with primary hyperparathyroidism. The results of localizing the abnormal glands by using 99mTc-MIBI were compared with those obtained by using thallium (Tl) 201-technetium (Tc) 99m (201Tl-99mTc) subtraction scintigraphy, computed tomography, and ultrasonography.
RESULTS: The delayed (2 hours) imaging of 99mTc-MIBI scintigraphy was highly useful for accurate localization of the abnormal parathyroid lesions. The diseased glands were detected in all cases where 99mTc-MIBI scintigraphy was used, and using 99mTc-MIBI scintigraphy provided more information than did computed tomography, ultrasonography, or 201Tl-99mTc subtraction scintigraphy.
CONCLUSION: This method is simple and essential for detecting hyperfunctioning parathyroid glands, especially those with small or ectopic lesions. This technique should be widely applied as a localizing diagnostic method for hyperparathyroidism.
METHODS: The usefulness of 99mTc-MIBI scintigraphy for detection of hyperfunctional parathyroid lesions was evaluated in 5 patients with primary hyperparathyroidism. The results of localizing the abnormal glands by using 99mTc-MIBI were compared with those obtained by using thallium (Tl) 201-technetium (Tc) 99m (201Tl-99mTc) subtraction scintigraphy, computed tomography, and ultrasonography.
RESULTS: The delayed (2 hours) imaging of 99mTc-MIBI scintigraphy was highly useful for accurate localization of the abnormal parathyroid lesions. The diseased glands were detected in all cases where 99mTc-MIBI scintigraphy was used, and using 99mTc-MIBI scintigraphy provided more information than did computed tomography, ultrasonography, or 201Tl-99mTc subtraction scintigraphy.
CONCLUSION: This method is simple and essential for detecting hyperfunctioning parathyroid glands, especially those with small or ectopic lesions. This technique should be widely applied as a localizing diagnostic method for hyperparathyroidism.