European journal of gastroenterology & hepatology · 2025
Patterns of pancreatic fatty infiltration on endoscopic ultrasound: in-depth characterization.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Keihanian Tara, Jawaid Salmaan A, Abidi Wasif A, Ayoub Fares, Patel Kalpesh K, Othman Mohamed O
Аннотация
BACKGROUND: Diffuse echogenicity of the pancreas (DEP) is a hallmark of endoscopic ultrasound (EUS) diagnosis of fatty pancreas. This study aimed to characterize different patterns of DEP seen on EUS and its correlation with clinical and laboratory values.
METHODS: This retrospective study includes patients diagnosed with fatty pancreas on EUS at a US tertiary center from January 2015 to June 2022. Fatty pancreas distribution was divided into three patterns: (a) The diffuse echogenicity of the entire pancreas with discrete hypoechoic areas 'indicative of fatty sparing areas', (b) diffuse echogenicity of the entire pancreas without any hypoechoic areas of fat sparing, and (c) diffuse echogenicity of the entire pancreas extending beyond the pancreatic border, 'cotton candy appearance'.
RESULTS: Overall, 238 patients were included (69.7% female). The average age of patients was 57.45 ± 12.93 years. The mean BMI was 31.27 ± 6.9 kg/m2. Concurrent diabetes and fatty liver were noted in 26.9 and 24.7% of the patients, respectively. The prevalence of exocrine pancreatic insufficiency (EPI) in those who underwent testing (n = 68) was 33.8%. Type II was the most observed type in our cohort (44.1%). Type I and III were seen in 26.1 and 29.8% of the cohort, respectively. The three types of fatty pancreas had similar clinical patterns, with comparable prevalence of diabetes (P = 0.9), fatty liver (P = 0.9), and EPI (P = 0.4).
CONCLUSION: The three patterns of DEP identified in this study have similar clinical and laboratory findings. Recognizing these patterns can aid in better detection of fatty pancreas.
METHODS: This retrospective study includes patients diagnosed with fatty pancreas on EUS at a US tertiary center from January 2015 to June 2022. Fatty pancreas distribution was divided into three patterns: (a) The diffuse echogenicity of the entire pancreas with discrete hypoechoic areas 'indicative of fatty sparing areas', (b) diffuse echogenicity of the entire pancreas without any hypoechoic areas of fat sparing, and (c) diffuse echogenicity of the entire pancreas extending beyond the pancreatic border, 'cotton candy appearance'.
RESULTS: Overall, 238 patients were included (69.7% female). The average age of patients was 57.45 ± 12.93 years. The mean BMI was 31.27 ± 6.9 kg/m2. Concurrent diabetes and fatty liver were noted in 26.9 and 24.7% of the patients, respectively. The prevalence of exocrine pancreatic insufficiency (EPI) in those who underwent testing (n = 68) was 33.8%. Type II was the most observed type in our cohort (44.1%). Type I and III were seen in 26.1 and 29.8% of the cohort, respectively. The three types of fatty pancreas had similar clinical patterns, with comparable prevalence of diabetes (P = 0.9), fatty liver (P = 0.9), and EPI (P = 0.4).
CONCLUSION: The three patterns of DEP identified in this study have similar clinical and laboratory findings. Recognizing these patterns can aid in better detection of fatty pancreas.