[Correlation between atherosclerosis--coronary disease and insulin resistance, regarded as the basis of metabolic syndrome].

AIM: To analyze the components of metabolic syndrome from patients with cardiovascular disease (myocardial infarction).

MATERIAL AND METHOD: Two groups of patients are included in this study-patients who have myocardial infarction (35) and patients who have myocardial infarction associated with diabetes mellitus (47). Patients, male and female are between 43 and 86 years. For these patients was studied: the presence of dyslipidemia, the control of diabetic disease, the pancreatic secretion (insulinemia, C peptid), the index of the insulin resistance, presence of obesity and HBP, proinflammatory status, value of homocystein and of GGT.

RESULTS: The most frequent component of metabolic syndrome was dyslipidemia. More patients had abnormal value of glycemia, the expression of an inefficient control of diabetic disease. Low levels of pancreatic secretion were found frequently in patients with glycoregulation disorder. Pathological value of insulin resistance index was found in the majority of patients with diabetes mellitus.

CONCLUSION: the patients with metabolic syndrome had a high risk of cardiovascular disease due to metabolic disorders (dyslipidemia, hyperglycemia) and proinflammatory status.