No shinkei geka. Neurological surgery · 2003
[Surgical stress in patients with asymptomatic unruptured intracranial aneurysms].
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ishiguro Tomoya, Yasui Toshihiro, Morikawa Tosie, Matsusaka Yasuhiro, Komiyama Masaki, Yamanaka Kazuhiro, Iwai Yoshiyasu
Аннотация
BACKGROUND: Surgical stress elicits a characteristic response involving induction of synthesis and release of acute-phase proteins such as C-reactive protein (CRP). To objectively evaluate the surgical stress in patients with asymptomatic unruptured intracranial aneurysms, serum levels of CRP after direct clipping via the pterional approach were measured.
METHODS: 42 patients who experienced an uneventful postoperative course, were evaluated according to age (less or more than 65 years old [adult or elderly]), aneurysmal location (middle cerebral artery territory [MC], anterior communicating artery [Acom] or internal carotid artery territory [IC]) and intraoperative trauma (positive or negative). We defined intraoperative trauma as intentional vein cutting, perforator vessel injury or suction of the gyrus rectus. All patients received standardized general anesthesia and were treated after the operations according to our standard protocols. Serum levels of CRP on postoperative day 2 were compared in each category.
RESULTS: Serum levels of CRP showed no significant difference between the adult group and the elderly group, but were greater in Acom patients than in MC and IC patients (p < 0.01, p < 0.05). As to intraoperative traumas, the positive group (almost all were intentional vein cutting) showed greater CRP levels than the negative group in MC and IC patients (p < 0.05). Operation time and volume of blood loss were almost the same in each category.
CONCLUSION: Our study shows that as far as serum levels of CRP are concerned, Acom location and vein cutting are the main factors of surgical stress in cases of unruptured aneurysms.
METHODS: 42 patients who experienced an uneventful postoperative course, were evaluated according to age (less or more than 65 years old [adult or elderly]), aneurysmal location (middle cerebral artery territory [MC], anterior communicating artery [Acom] or internal carotid artery territory [IC]) and intraoperative trauma (positive or negative). We defined intraoperative trauma as intentional vein cutting, perforator vessel injury or suction of the gyrus rectus. All patients received standardized general anesthesia and were treated after the operations according to our standard protocols. Serum levels of CRP on postoperative day 2 were compared in each category.
RESULTS: Serum levels of CRP showed no significant difference between the adult group and the elderly group, but were greater in Acom patients than in MC and IC patients (p < 0.01, p < 0.05). As to intraoperative traumas, the positive group (almost all were intentional vein cutting) showed greater CRP levels than the negative group in MC and IC patients (p < 0.05). Operation time and volume of blood loss were almost the same in each category.
CONCLUSION: Our study shows that as far as serum levels of CRP are concerned, Acom location and vein cutting are the main factors of surgical stress in cases of unruptured aneurysms.