Use of Octreotide in Chylothorax With Mediastinal Mass of Unknown Behaviour: A Case Report.

Chylothorax poses a clinical challenge, especially in resource-limited settings where diagnosis and treatment require innovation. This report details the successful use of octreotide in a 37-year-old female with non-traumatic chylothorax secondary to a mediastinal mass. She presented with chylothorax symptoms, and imaging showed a mediastinal mass, but tissue biopsy was refused, and advanced interventions were unavailable. Octreotide infusion reduced chest tube output and led to the complete resolution of chylothorax. This case demonstrates that octreotide can provide effective symptom control and clinical stabilisation in mediastinal mass-associated chylothorax when surgical or advanced options are not feasible, serving as a bridge for further workup and treatment planning.