Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology · 2017
Neurolymphomatosis: A Surreal Presentation of Lymphoma.
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Khandelwal Shikha, Saxena Suvinay, Hansalia Disha J
Аннотация
BACKGROUND: Neurolymphomatosis is a neurologic complication poorly recognized by neurologists and oncologists and presents usually several months after successful treatment of systemic lymphoma. Other disorders that must be differentiated from these entities include peripheral-nerve or nerve root compression and paraneoplastic neuropathy.
AIM: To describe the unusual occurrence of neurolymphomatosis in a patient of B-cell lymphoma.
METHOD: Diagnosis was made by demonstration of enhancement of nerve roots on Magnetic Resonance Imaging of the brachial, lumbosacral plexus, peripheral nerves or by increased hyper-metabolic activity along the course of affected nerves on fluorodeoxyglucose positron emission tomography (FDG-PET).
RESULTS AND CONCLUSION: MRI and PET-CT are imaging modalities of choice for evaluation of patients with lymphoma and suspected neural involvement. Treatment of neurolymphomatosis consists of focal radiotherapy and high-dose methotrexate therapy.
AIM: To describe the unusual occurrence of neurolymphomatosis in a patient of B-cell lymphoma.
METHOD: Diagnosis was made by demonstration of enhancement of nerve roots on Magnetic Resonance Imaging of the brachial, lumbosacral plexus, peripheral nerves or by increased hyper-metabolic activity along the course of affected nerves on fluorodeoxyglucose positron emission tomography (FDG-PET).
RESULTS AND CONCLUSION: MRI and PET-CT are imaging modalities of choice for evaluation of patients with lymphoma and suspected neural involvement. Treatment of neurolymphomatosis consists of focal radiotherapy and high-dose methotrexate therapy.