[About early preclinical diagnosis of gastroduodenal pathology upon exposure to environmental factors].

The paper presents new screening capacities for the early detection of gastroduodenal diseases. The GastroPanel diagnostic system can determine the functional state and indirectly the mucosal structure of different segments of the stomach from blood tests using the enzyme immunoassay. The system permits Helicobacter pylori infection to be detected. Helicobacter pylori is well-known to be the principal cause of the most common gastroduodenal diseases, such as chronic gastritis, including atrophic gastritis regarded as precancer, as well as ulcerative disease of the stomach and duodenum, and distal gastric cancer. The GastroPanel test system is informative, low-informative, and acceptable for the stomach to be evaluated during population-based surveys. It enables gastroduodenal disease to be suspected at the preclinical stage. The GastroPanel test system opens up possibilities for investigating the chronic exposure of the stomach to poor environmental factors over time.