Zhonghua yi xue za zhi · 2016
[Cheek blood sampling of mice].
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Zhang Shuaishuai, Li Tianshou, Zang Meirong, Qiu Lugui
Аннотация
OBJECTIVE: To explore the method of cheek blood sampling in mice in continuous blood test.
METHODS: Cheek blood sampling was carried out in 10 9-week-old mice once every 2-3 days. The volumes of blood samples were recorded. Reactions of the mice were observed.
RESULTS: Cheek blood sampling collected 0.3-0.6 ml of blood every time, and did not affect the normal activities of the mice. The blood sampling could be repeated every 2-3 days.
CONCLUSIONS: Cheek blood sampling has several advantages including being capable to draw adequate blood, simple and easy to operate, well tolerated, and ethical in treating laboratory animals.
METHODS: Cheek blood sampling was carried out in 10 9-week-old mice once every 2-3 days. The volumes of blood samples were recorded. Reactions of the mice were observed.
RESULTS: Cheek blood sampling collected 0.3-0.6 ml of blood every time, and did not affect the normal activities of the mice. The blood sampling could be repeated every 2-3 days.
CONCLUSIONS: Cheek blood sampling has several advantages including being capable to draw adequate blood, simple and easy to operate, well tolerated, and ethical in treating laboratory animals.