Corvis ST parameters in eyes with primary angle-closure glaucoma: a retrospective cross-sectional study using propensity score matching.

BACKGROUND

To evaluate differences in Corvis ST tonometry (CST) parameters between healthy eyes and eyes with primary angle-closure glaucoma (PACG).

METHODS

We retrospectively analyzed CST parameters of 24 healthy eyes and 24 eyes with PACG after 1:1 propensity score matching based on age, sex, axial length, intraocular pressure, and central corneal thickness. Differences in 12 CST parameters were evaluated using linear mixed-effects models, with group as a fixed effect and subject ID as a random intercept to account for inter-eye correlation. The models were adjusted for age, sex, axial length, intraocular pressure, and central corneal thickness. Multiple comparisons across parameters were controlled using the Benjamini–Hochberg false discovery rate procedure.

RESULTS

Compared with healthy eyes, eyes with PACG exhibited greater A1 deformation amplitude and a shorter A2 time.

CONCLUSIONS

Compared with healthy eyes, eyes with PACG showed differences in selected CST parameters, specifically greater A1 deformation amplitude and shorter A2 time. These findings may indicate altered corneal dynamic response behavior in PACG.