[Experiences with intranasal and parenteral use of 1-desamino-8-D-arginine vasopressin (DDAVP). Use in the diagnosis of hypophyseal function].

While 1-desamino-8-D-arginine-vasopressin is not suitable for the functional diagnostics of the anterior pituitary gland, it has as in the therapy of the central diabetes insipidus a firm place also in its diagnostics. A hypothalamic neurohypophyseal system was demonstrated. Apart from a secure diagnostic evidence the test shows further advantages in comparison to the hitherto performed methods: an essentially smaller load for patient and personnel, a shorter duration and a simplified performance. First findings in patients with central diabetes insipidus, in a female patient with renal diabetes insipidus and patient without disturbance of the water balance are discussed. A control of our findings in other institutions is desirable.