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DOI 10.1016/j.ijgo.2008.03.020

Медицинская библиотека · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2008

Effect of sildenafil on clitoral blood flow and sexual response in postmenopausal women with orgasmic dysfunction.

Cavalcanti Ana L, Bagnoli Vicente R, Fonseca Angela M, Pastore Roberto A, Cardoso Eduardo B, Paixão Jucilene S, Soares José M, Saad Fabrício, Baracat Edmund C

СтатьяРандомизированное исследованиеПеревод в очереди

Аннотация

OBJECTIVE

To analyze the effects of sildenafil citrate on clitoral blood flow and sexual response in postmenopausal women with orgasmic dysfunction.

METHOD: In this randomized, double-blind, placebo-controlled trial 22 women received a 50-mg dose of sildenafil (n=11) or placebo (n=11) daily for 15 days. The Golombok Rust Inventory of Sexual Satisfaction (GRISS) was used for subjective evaluation of the sexual-response cycle. Clitoral blood flow was measured by color and pulse Doppler at baseline, after 1 hour of taking the first dose, and after 15 days of treatment.

RESULTS

Blood flow was significantly more improved in the sildenafil than in the placebo group (P<0.05), and a positive correlation between Doppler values and GRISS scores was noted in the sildenafil group after only 15 days of treatment.

CONCLUSION

Sildenafil may improve clitoral blood flow and increase the GRISS scores in postmenopausal women with orgasmic dysfunction.

Для цитирования: Cavalcanti Ana L, Bagnoli Vicente R, Fonseca Angela M, Pastore Roberto A, Cardoso Eduardo B, Paixão Jucilene S, Soares José M, Saad Fabrício, Baracat Edmund C. Effect of sildenafil on clitoral blood flow and sexual response in postmenopausal women with orgasmic dysfunction.. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. 2008. DOI: 10.1016/j.ijgo.2008.03.020.

Предметные рубрики MeSH

Blood Flow VelocityClitorisDouble-Blind MethodFemaleHumansMiddle AgedPersonal SatisfactionPiperazinesPostmenopausePurinesRegional Blood FlowSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalSildenafil CitrateSulfonesUltrasonography, Doppler, ColorUltrasonography, Doppler, PulsedVasodilator Agents
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