Clinical biochemistry · 2008
Post-methionine load test: A more sensitive tool to reveal hyperhomocysteinemia in Alzheimer patients?
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Galimberti Gloria, Conti Elisa, Zini Michela, Piazza Fabrizio, Fenaroli Francesco, Isella Valeria, Facheris Maurizio, Perlangeli Vittoria, Antolini Laura, DeFilippi Francesco, Ferrarese Carlo
Аннотация
OBJECTIVE: To identify the real number of hyperhomocysteinemic Alzheimer's patients who may benefit from homocysteine-lowering therapy.
METHODS: Basal and post-methionine load homocysteine levels were assessed by rp-HPLC system.
RESULTS: PML test revealed twice as many hyperhomocysteinemic AD subjects with respect to the fasting analysis.
CONCLUSION: PML test resulted useful in detecting higher number of hyperhomocysteinemic AD patients who may have the chance of an early folate treatment.
METHODS: Basal and post-methionine load homocysteine levels were assessed by rp-HPLC system.
RESULTS: PML test revealed twice as many hyperhomocysteinemic AD subjects with respect to the fasting analysis.
CONCLUSION: PML test resulted useful in detecting higher number of hyperhomocysteinemic AD patients who may have the chance of an early folate treatment.