[New modes of insulin delivery and new modes of monitoring of type 1 diabetes mellitus].

New modes of insulin delivery and new modes of monitoring of type 1 diabetes mellitus. Insulin therapy in type 1 diabetes aims at keeping blood glucose level in a near-normal range. Basal-bolus regimen using multiple daily injections of insulin analogues or, with higher flexibility and precision, an insulin pump fulfils the coverage of basal needs and those related to food intakes. The patch-pumps, discrete and catheter-free, promote the use of continuous insulin delivery. Moving to intra-peritoneal route provides a solution to patients with extreme glucose variability. The combination of continuous glucose monitoring to insulin pumps has opened the way toward glucose-driven insulin therapy, which showed its efficacy in the reduction of hypoglycemia, and more recently on total glucose control through the first hybrid artificial pancreas.