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DOI 10.3389/fonc.2026.1889467

Медицинская библиотека · Frontiers in oncology · 2026

Breast implant-associated anaplastic large cell lymphoma: a case report and literature review.

Qi Shuangyi, Liu Hu, Huang Qidi, Gu Huayan, Ding JiaLing, Guo Guilong, Zheng Shurong

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Аннотация

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare T-cell non-Hodgkin lymphoma primarily associated with textured breast implants. Its pathological hallmarks include CD30 positivity, ALK negativity, and clonal T-cell receptor gene rearrangement. Complete surgical excision is the primary treatment modality, and early diagnosis combined with standardized management is associated with a favorable prognosis. We report a case of BIA-ALCL in a 47-year-old female who presented with breast swelling 20 years after receiving textured breast implants. To the best of our knowledge, this is the first documented case of BIA-ALCL in mainland China. Preoperative aspiration was not suggestive of BIA-ALCL, and the diagnosis was ultimately confirmed through histopathological examination of the capsule tissue. Based on a comprehensive postoperative systemic evaluation, no adjuvant therapy was required.

Для цитирования: Qi Shuangyi, Liu Hu, Huang Qidi, Gu Huayan, Ding JiaLing, Guo Guilong, Zheng Shurong. Breast implant-associated anaplastic large cell lymphoma: a case report and literature review.. Frontiers in oncology. 2026. DOI: 10.3389/fonc.2026.1889467.
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