[A Case of Huge Infectious Gastrointestinal Stromal Tumor of the Stomach Undergoing Primary Tumor Resection after Endoscopic Drainage].

A 77-year-old man presented to our hospital with anemia and was diagnosed with a high-risk gastrointestinal stromal tumor (GIST)of the stomach on abdominal CT scan and endoscopic ultrasound-guided fine-needle biopsy. One month after initiating the neoadjuvant imatinib therapy, the patient was admitted to our hospital for fever and was diagnosed with an intratumoral infection. Antibiotic therapy was immediately initiated, and upper gastrointestinal endoscopy revealed a fistula between the stomach and tumor; therefore, endoscopic drainage was performed through the fistula. A local gastrectomy was performed 6 days after draining the intratumoral abscess as the inflammatory findings improved rapidly. The patient was discharged on day 6 without any postoperative complications. Adjuvant therapy with imatinib was initiated 6 weeks after surgery and is ongoing without any recurrence 14 months later. Gastric GISTs rarely develop into intratumoral infections, and appropriate treatment has not been established. In this case, the infection was controlled using antibiotics and endoscopic drainage, and resection was performed immediately after controlling the infection. Here, we report the treatment of infectious GIST with a review of the literature.