The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2006
BiPAP in early guillain-barré syndrome may fail.
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Wijdicks Eelco F M, Roy Tuhin K
Аннотация
BACKGROUND: Non-invasive mechanical ventilation (BiPAP) has been introduced for use in neuromuscular respiratory disease such as amyotrophic lateral sclerosis and myasthenia gravis. There is no experience in Guillain-Barré syndrome.
METHODS: We describe for the first time the use of BiPAP to assist in the work of breathing in two consecutive patients with progressing Guillain-Barré syndrome (GBS) and marginal pulmonary function.
RESULTS: Our initial attempts to use BiPAP in GBS and early neuromuscular respiratory failure were totally unsuccessful. There was marked initial improvement; however, emergency intubation was needed in both patients, one of which became acutely cyanotic.
CONCLUSIONS: Until more experience is available, we strongly warn against using BiPAP in deteriorating patients with GBS.
METHODS: We describe for the first time the use of BiPAP to assist in the work of breathing in two consecutive patients with progressing Guillain-Barré syndrome (GBS) and marginal pulmonary function.
RESULTS: Our initial attempts to use BiPAP in GBS and early neuromuscular respiratory failure were totally unsuccessful. There was marked initial improvement; however, emergency intubation was needed in both patients, one of which became acutely cyanotic.
CONCLUSIONS: Until more experience is available, we strongly warn against using BiPAP in deteriorating patients with GBS.