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DOI 10.1007/s10815-007-9165-2

Медицинская библиотека · Journal of assisted reproduction and genetics · 2007

The possible role of hyperhomocysteinemia on IVF outcome.

Pacchiarotti Arianna, Mohamed Mohamed A, Micara Giulietta, Linari Antonella, Tranquilli Daniela, Espinola Salomè B, Aragona Cesare

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Аннотация

PURPOSE: To evaluate the effect of the hyperhomocysteinemia on pregnancy rate, implantation rate and abortion rate after IVF.

METHOD: Data from a total of 48 infertile couples with hyperhomocysteinemia were prospectively collected for this study. All patients underwent a standard down regulation protocol for ovarian stimulation. Oocytes recovery was performed at 36 h after hCG administration. Embryo transfer took place at 48 h after insemination. The patients were matched in two groups that received or did not receive therapy (group A and B respectively) to normalize homocysteine plasma level.

RESULTS

Pregnancy rate, implantation rate and abortion rate varied significantly (p<or=0.05) between the two groups. The number and quality of embryos transferred did not differ between the groups.

CONCLUSION

The results suggest that hyperhomocysteinemia could affect IVF outcome.

Для цитирования: Pacchiarotti Arianna, Mohamed Mohamed A, Micara Giulietta, Linari Antonella, Tranquilli Daniela, Espinola Salomè B, Aragona Cesare. The possible role of hyperhomocysteinemia on IVF outcome.. Journal of assisted reproduction and genetics. 2007. DOI: 10.1007/s10815-007-9165-2.

Предметные рубрики MeSH

Abortion, SpontaneousAdultEmbryo ImplantationFemaleFertilization in VitroHumansHyperhomocysteinemiaPregnancyPregnancy OutcomePregnancy Rate
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