Comparative Evaluation of the Efficacy of Triclosan-Coated and Chlorhexidine-Coated Suture on Bacterial Load Reduction in Periodontal Flap Surgery: A Clinicomicrobiological Study.
Аннотация
BACKGROUND
Sutures are essential for wound closure but may facilitate microbial colonization, increasing the risk of surgical site infections. Antibacterial-coated sutures, such as triclosan (TCS) and chlorhexidine (CCS), have been developed to mitigate this concern.
MATERIALS AND
METHODS
A double-blind, randomized clinical trial was conducted on 20 patients undergoing periodontal flap surgery, comparing TCS and CCS. Healing was assessed on postoperative day 8 using Landry's Healing Index; microbial burden was quantified through CFU enumeration and Gram staining.
RESULTS
Healing scores were comparable between groups (TCS: 4.1 ± 0.7; CCS: 3.9 ± 0.7; P = 0.63). However, CCS exhibited significantly lower CFU counts (0.011 × 106 ± 0.031 × 106) than TCS (4.3 × 106 ± 4.8 × 106) (P < 0.001). Gram staining revealed polymicrobial oral flora in both groups.
CONCLUSION
Chlorhexidine-coated sutures exhibited superior antimicrobial efficacy without compromising early wound healing.
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