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DOI 10.4103/jpbs.jpbs_1288_25

Медицинская библиотека · Journal of pharmacy & bioallied sciences · 2025

Comparative Evaluation of the Efficacy of Triclosan-Coated and Chlorhexidine-Coated Suture on Bacterial Load Reduction in Periodontal Flap Surgery: A Clinicomicrobiological Study.

Choudhary Megha, Bhatnagar Shruti, Bagde Hiroj, Savitha A N, Radke Vrishali, Rathi Ritika

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Аннотация

BACKGROUND

Sutures are essential for wound closure but may facilitate microbial colonization, increasing the risk of surgical site infections. Antibacterial-coated sutures, such as triclosan (TCS) and chlorhexidine (CCS), have been developed to mitigate this concern.

MATERIALS AND

METHODS

A double-blind, randomized clinical trial was conducted on 20 patients undergoing periodontal flap surgery, comparing TCS and CCS. Healing was assessed on postoperative day 8 using Landry's Healing Index; microbial burden was quantified through CFU enumeration and Gram staining.

RESULTS

Healing scores were comparable between groups (TCS: 4.1 ± 0.7; CCS: 3.9 ± 0.7; P = 0.63). However, CCS exhibited significantly lower CFU counts (0.011 × 106 ± 0.031 × 106) than TCS (4.3 × 106 ± 4.8 × 106) (P < 0.001). Gram staining revealed polymicrobial oral flora in both groups.

CONCLUSION

Chlorhexidine-coated sutures exhibited superior antimicrobial efficacy without compromising early wound healing.

Для цитирования: Choudhary Megha, Bhatnagar Shruti, Bagde Hiroj, Savitha A N, Radke Vrishali, Rathi Ritika. Comparative Evaluation of the Efficacy of Triclosan-Coated and Chlorhexidine-Coated Suture on Bacterial Load Reduction in Periodontal Flap Surgery: A Clinicomicrobiological Study.. Journal of pharmacy & bioallied sciences. 2025. DOI: 10.4103/jpbs.jpbs_1288_25.
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