Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians · 2007
Oral eosinophilic granulomas in tigers (Panthera tigris)--a collection of 16 cases.
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Sykes John M, Garner Michael M, Greer Leah L, Lung Nancy P, Coke Rob L, Ridgley Frank, Bush Mitch, Montali Richard J, Okimoto Ben, Schmidt Robert, Allen Jack L, Rideout Bruce A, Pesavento Patricia A, Ramsay Edward C
Аннотация
Oral eosinophilic granulomas were diagnosed in 16 tigers (Panthera tigris). All lesions were located on the hard or soft palate and typically consisted of flat or slightly raised circular ulcers. Histologic features of these lesions were essentially identical to those seen in oral eosinophilic granulomas of domestic cats and dogs. No clinical signs were noted in eight cases, though various degrees of inappetence, excessive salivation, and dysphagia were noted in the other eight tigers. Six cases were not treated. Treatment for the remaining 10 cases centered on corticosteroids and additional treatments included surgical removal, cryotherapy, antibiotics, and chlorpheniramine. Treatment with corticosteroids did appear to be effective in some cases, though lesions would worsen after cessation of therapy and no cases were cured. In addition, three cases developed complications possibly related to this corticosteroid therapy. The etiology of these lesions remains unknown, though an underlying allergic condition is likely.