[Effect of autonomic denervation on the secretory function of submandibular glands].

Submandibular gland is innervated by sympathetic and parasympathetic nerves, both of which work synergistically to promote the salivation of the glands. However, denervation does not always produce an inhibitive effect. Regeneration secretion was put forward to describe the situation in which the glands after denervation were found to be supersensitive to the stimulation of several agonists of saliva secretion-related receptors. It is of clinical significance to get a good understanding of the secretory mechanism changes in the autonomically denervated submandibular gland. The present paper aims to review the studies on the denervation effects on the submandibular gland.