Detection of early atherosclerosis by analysis of ultrasonic Doppler signals produced by mural flow disturbances.

The paper describes an in vitro study using a multi-gate Doppler ultrasound system to investigate flow disturbances in a blood analogue caused by small stenoses (2-25% cross-sectional area reduction), using steady flow (100-600 ml min-1) in a 6 mm diameter rigid artery model. The results indicate that stenoses greater than 5% were detectable.