The journal of evidence-based dental practice · 2010
Periodontal disease is related to local and systemic mediators of inflammation.
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Dasanayake Ananda P
Аннотация
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Local and systemic biomarkers in gingival crevicular fluid increase odds of periodontitis. Fitzsimmons TR, Sanders AE, Bartold PM, Slade GD. J Clin Periodontol 2010;37(1):30-6.
REVIEWER: Ananda P. Dasanayake, BDS, MPH, PhD, FACE.
PURPOSE/QUESTION: The authors attempted to study the independent and combined effects of local (IL-1β) and systemic (CRP) inflammatory biomarkers in gingival crevicular fluid (GCF) on the risk of periodontitis.
SOURCE OF FUNDING: Government: National Health and Medical Research Council (NHMRC) of Australia and NHMRC Sidney Sax Public Health Fellowship.
TYPE OF STUDY/DESIGN: Case-control study.
LEVEL OF EVIDENCE: Level 2: Limited-quality, patient-oriented evidence.
STRENGTH OF RECOMMENDATION GRADE: Not applicable.
REVIEWER: Ananda P. Dasanayake, BDS, MPH, PhD, FACE.
PURPOSE/QUESTION: The authors attempted to study the independent and combined effects of local (IL-1β) and systemic (CRP) inflammatory biomarkers in gingival crevicular fluid (GCF) on the risk of periodontitis.
SOURCE OF FUNDING: Government: National Health and Medical Research Council (NHMRC) of Australia and NHMRC Sidney Sax Public Health Fellowship.
TYPE OF STUDY/DESIGN: Case-control study.
LEVEL OF EVIDENCE: Level 2: Limited-quality, patient-oriented evidence.
STRENGTH OF RECOMMENDATION GRADE: Not applicable.