[The pathogenetic aspects of an ulcerative lesion of the duodenal mucosa].

Basing upon the histochemical study of SDG and NO-synthase activity in 68 biopsies taken from patients with duodenal ulcer the connection between the clinical specificity and the activity of the disease the SDG activity decreases, while that of NO-synthase increases. At the phase of cicatrization the opposite process is going on. The authors connect the phenomena under investigation with the vasodilatory and protective abilities of the nitrogen oxide.