Gastroenterologia y hepatologia · 2011
[Signet ring cell carcinoma of the ampulla of Vater].
Клинический случайАннотация на английскомСтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
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García Aurora Burgos, Arranz Eduardo Martín, Sanz Rafael Rey, Serrano Eva Marín, Arranz María Dolores Martín, Sanz-Agero Paloma González, Bellido Elena Collantes, Kreilinger José Juan Pozo, Prianes Luis Asensio, Juberías Luis Alberto Mata, Robledo Juan Pedro Pérez, Parga José Manuel Suárez, Cabral José María Segura
Аннотация
INTRODUCTION: Signet ring cell carcinoma of the ampulla of Vater is a rare entity and less than 20 cases have been described in the literature. We report the cases of two patients with this disease and provide a literature review of previous studies.
CASE REPORT: We describe two patients with obstructive jaundice. Abdominal ultrasonography and abdominal computed tomography showed dilatation of the intrahepatic and common bile duct. Duodenoscopy indicated a protruding mass on the ampulla of Vater. Histopathological examination showed round cells and their nuclei were located on one side with prominent signet-ring features. One patient underwent a cephalic pancreatoduodenectomy with lymphadenectomy and the other a total pancreatectomy.
DISCUSSION: Signet ring cell carcinoma of the ampulla of Vater has only been described in isolated cases in the literature. Therefore, the clinicopathological features and prognosis of this disease have not yet been well defined.
CASE REPORT: We describe two patients with obstructive jaundice. Abdominal ultrasonography and abdominal computed tomography showed dilatation of the intrahepatic and common bile duct. Duodenoscopy indicated a protruding mass on the ampulla of Vater. Histopathological examination showed round cells and their nuclei were located on one side with prominent signet-ring features. One patient underwent a cephalic pancreatoduodenectomy with lymphadenectomy and the other a total pancreatectomy.
DISCUSSION: Signet ring cell carcinoma of the ampulla of Vater has only been described in isolated cases in the literature. Therefore, the clinicopathological features and prognosis of this disease have not yet been well defined.
Предметные рубрики MeSH
AgedAmpulla of VaterAntimetabolites, AntineoplasticCarcinoma, Signet Ring CellChemotherapy, AdjuvantCholangiopancreatography, Endoscopic RetrogradeCombined Modality TherapyCommon Bile Duct NeoplasmsDeoxycytidineHumansJaundice, ObstructiveJejunumLiverLymphoma, FollicularMaleNeoplasm InvasivenessNeoplasms, Second PrimaryPancreatectomyPancreaticoduodenectomySplenectomyUrinary Bladder NeoplasmsGemcitabine