Small common bile duct - the risk factor for post-ERCP pancreatitis in patients with choledocholithiasis.

OBJECTIVE

Aim: To investigate the risk factors for PEP in patients with choledocholithiasis.

PATIENTS AND

METHODS

Materials and

Methods

We have retrospectively analyzed 253 cases with choledocholithiasis that underwent ERCP. The primary endpoint was the occurrence of PEP. A number of potential risk factors for PEP were taken into account: gender, age ( 10 mm); type of choledocholithiasis - microcholedocholithiasis, choledocholithiasis (1-2 stones), multiple choledocholithiasis (≥ 3 stones) and choledocholithiasis due to Mirizzi syndrome; periampullary diverticulum; papilla size (≤5 or >6 mm); ERCP success; selective biliary cannulation; pancreatic cannulation/injection; precut; papillotomy.

RESULTS

Results

PEP was in 8 (3,2 %) cases. Univariate analysis identified two factors associated with PEP - common bile duct ≤10 mm (P=0.045) and papilla ≤5 mm (P=0.036). In multivariate analysis, among all variables only the common bile size ≤10 mm appeared to be significant (P=0.018).

CONCLUSION

Conclusions

In patients with choledocholithiasis the occurrence of PEP is related to common bile duct size less than 10 mm.