[Troponin and its diagnostic values in ischemic heart disease].

The determination of biochemical markers of myocardial injury plays beside the electrocardiographic changes and the clinical signs the significant role in acute coronary syndromes. The most specific and sensitive markers are cardiac isoforms of troponin I and T. The advantages of troponins level determination should be considered in the cases of inconclusive results of the conventional markers, for example during surgical procedures. This applies especially to the cardiac surgery. The serum troponin concentration is elevated in many cases of unstable angina pectoris and is an important predictor of acute cardiovascular events and sudden death. This method allows also assessment of therapeutic success of reperfusion therapy and predicts potency of infarct related artery. The use of platelets receptors IIb/IIIa inhibitors or low molecular weight heparin in the case of troponins elevation was identified to improve the patients prognosis. The clinical value of troponins level determination in acute coronary syndromes was discussed in this paper.