Moderately hypofractionated post-operative radiation therapy for breast cancer: preferences amongst radiation oncologists from countries in Latin America and the Caribbean.
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Marta Gustavo Nader, Moraes Fabio Y, de Oliveira Franco Rejane Carolina, de Andrade Carvalho Heloísa, Gouveia André Guimaraes, de Lima Gössling Gustavo Cartaxo, de Jesus Rafaela Gomes, Ferraris Gustavo, Schuffenegger Pablo Munoz, Bardales Gustavo Sarria, Chacón María Adela Poitevin, Murillo Raúl, Sánchez Luis Ernesto Moreno, Gamarra-Cabezas Elizabeth, Rosa Arthur Accioly, da Silva Maurício Fraga, de Mattos Marcos Duarte, Morais Diego Chaves Rezende, de Castro Douglas Guedes, Dal Pra Alan, Amêndola Beatriz E, Barros José Máximo, Lara Tomas Merino, Isa Nicolás, de la Mata Moya Dolores, Hidalgo Iván, Velilla Diego Gimenez, Loayza Lijia Elizabeth Avilés, Montenegro Francisco Gomez, Sanchez Chacin Nestor O, Werutsky Gustavo, Viani Gustavo Arruda
Аннотация
MATERIALS AN METHODS: Radiation oncologists from LAC were invited to contribute to this study. A 38-question survey was used to evaluate their opinions.
RESULTS: A total of 173 radiation oncologists from 13 countries answered the questionnaire. The majority of respondents (84.9%) preferred moderately hypofractionated post-operative radiation therapy as their first choice in cases of whole breast irradiation. Whole breast plus regional nodal irradiation, post-mastectomy (chest wall and regional nodal irradiation) without reconstruction, and post-mastectomy (chest wall and regional node irradiation) with reconstruction hypofractionated post-operative radiation therapy was preferred by 72.2% 71.1%, and 53.7% of respondents, respectively. Breast cancer stage, and flap-based breast reconstruction were the factors associated with absolute contraindications for the use of hypofractionated schedules.
CONCLUSION: Even though moderately hypofractionated post-operative radiation therapy for breast cancer is considered a new standard to the vast majority of the patients, its unrestricted application in clinical practice across LAC still faces reluctance.