Circulation. Cardiovascular interventions · 2026
Transcatheter Mitral and Aortic Paravalvular Leak Closure: Innovations, Challenges, and Future Directions.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ruberti Andrea, Flores-Umanzor Eduardo, Sanchis Laura, Pilgrim Thomas, Regueiro Ander, Garot Philippe, Ibrahim Reda, Velazquez Guillermo, Smolka Grzegorz, Abdul-Jawad Altisent Omar, Cepas-Guillén Pedro, Hascoët Sebastien, Occhipinti Giovanni, Cruz-Gonzalez Ignacio, Sitges Marta, Vidal Barbara, Martí-Aguasca Gerard, Onorato Eustaquio Maria, Osten Mark, Rodes-Cabau Josep, Toth Gabor G, Dumonteil Nicolas, Calvert Patrick A, Horlick Eric, Freixa Xavier
Аннотация
Paravalvular leak (PVL) is a well-known complication of valve replacement, occurring in up to 10% of aortic and 17% of mitral prosthetic valves. Although many leaks are small and clinically insignificant, ≈1% to 5% of cases are associated with clinically relevant complications, such as heart failure symptoms and hemolytic anemia. Surgical reoperation is currently considered the first-line option; however, it encompasses high mortality and morbidity risks. In the past years, transcatheter PVL closure has proven to be highly effective when performed in experienced centers. Transcatheter PVL closure requires advanced imaging modalities, specialized materials, and techniques, reflecting the high complexity of the procedure. We review the complex nature of PVL, including its diagnostic workup and the available transcatheter treatment strategies, with a special focus on the treatment of mitral and aortic PVL using plugging devices.