Molecularly Imprinted Membranes for Selective Biomarker Recognition: Recent Advances and Emerging Strategies.

Molecularly imprinted membranes (MIMs) epitomize the convergence of membrane science with molecular imprinted technology. Endowed with intrinsic molecular recognition and memory functionalities, MIMs have the potential to evolve into pivotal tools for the selective separation, identification, and purification of biomolecules. This review summarizes the forefront advancements in the selective recognition and separation of macromolecular biomarkers through MIMs, such as proteins, peptides, and nucleotides. A comprehensive overview of diverse imprinting polymerization methodologies employed in crafting MIMs tailored for specific biomacromolecule targets is presented. Additionally, the evolving research landscape concerning MIMs as a potent platform for the targeted capture of biomacromolecule-associated biomarkers is critically appraised and is discussed.