Gan to kagaku ryoho. Cancer & chemotherapy · 2016
[A Case of Pure Squamous Cell Carcinoma of the Breast in an Elderly Woman Diagnosed by Cytology].
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Sato Yasufumi, Inatome Junichi, Okishiro Masatsugu, Oneda Yasuo, Ishida Tomo, Morimoto Yoshihiro, Kuwahara Ryuichi, Kusama Hiroki, Naito Atsushi, Murakami Kohei, Katsura Yoshiteru, Ohmura Yoshiaki, Kagawa Yoshinori, Takeno Atsushi, Egawa Chiyomi, Takeda Yutaka, Kato Takeshi, Tamura Shigeyuki, Takatsuka Yuichi, Goto Takayoshi, Nagano Teruaki, Nakatsuka Shinichi
Аннотация
A n 85-year-old woman presented with a mass in the left breast. A3 7mm lobulated mass including enhancement of a cyst of 37mm was detected by sonography. An axillary lymph node had increased to 16 mm. Atypical cells dyed by light green and orange G were identified by fine needle aspiration and cytology. She was diagnosed with left breast cancer(cT2N1M0, Stage II B), histologically suspected to be squamous cell carcinoma. She underwent a left-breast-conserving surgery and axillary lymph node dissection. On pathology, a cyst of 34×30mm was noted. The tumor grew from inside the cyst to the surround- ing tissue and it had a trend for keratinocytes. Lymph node metastases affected 1/11. By immunostaining, the tumor was found to be ER(+), PgR(-), HER2(-), CK5/6(+), p40(+), mammaglobin(-), and GCDFP15(-). There was no component of ductal carcinoma. She received radiotherapy to the left breast and tamoxifen as an adjuvant therapy. Squamous cell carcinoma of the breast is rare. We encountered a case of pure squamous cell carcinoma of the breast in an elderly woman. We report this case with a discussion of the relevant literature.