Clinica chimica acta; international journal of clinical chemistry · 2020
Prognostic significance of preoperative circulating FAR and FCI scores in patients with ovarian cancer.
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Wang Huige, Shen Yanjun, Ding Xiaoyan, Ding Yongfen, Cheng Ling, Lai Juan
Аннотация
BACKGROUND: Ovarian malignancy is among the most common lethal cancers in gynaecology. It has been considered that nutrition status and inflammation are two essential factors associated with the poor survival rates of patients suffering from multiple tumours.
METHODS: This research included 174 subjects who suffered from FIGO stage I-IV OC and underwent surgeries between May 2008 and March 2013.
RESULTS: The results showed that FAR, T3-T4 depth, high CA125, stage III-IV and metastasis were highly associated with low overall survival rates. Moreover, higher FCI was markedly correlated with decreased survival in patients with OC.
CONCLUSIONS: The combination of FAR and CA125 could be a new non-invasive marker in blood and probably assist physicians in evaluating the prognosis of patients.
METHODS: This research included 174 subjects who suffered from FIGO stage I-IV OC and underwent surgeries between May 2008 and March 2013.
RESULTS: The results showed that FAR, T3-T4 depth, high CA125, stage III-IV and metastasis were highly associated with low overall survival rates. Moreover, higher FCI was markedly correlated with decreased survival in patients with OC.
CONCLUSIONS: The combination of FAR and CA125 could be a new non-invasive marker in blood and probably assist physicians in evaluating the prognosis of patients.