Journal of pediatric hematology/oncology · 2013
Raising awareness of non-Hodgkin lymphoma in HIV-infected adolescents: report of 2 cases in the HAART era.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Zangari Paola, Santilli Veronica, Cotugno Nicola, Manno Emma, Palumbo Giuseppe, Lombardi Alessandra, De Vito Rita, Tchidjou Hyppolite, Baldassari Stefania, Ariganello Paola, Pontrelli Giuseppe, De Florio Francesca, Palma Paolo, Bernardi Stefania
Аннотация
Human immunodeficiency virus (HIV) chronically infected patients are at increased risk of developing non-Hodgkin lymphoma compared with the general population. Highly active antiretroviral therapy has had a dramatic effect on the natural history of HIV infection, reducing the incidence of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma and improving overall survival. However, problems related to adherence to treatment, frequently experienced during adolescence, may increase the risk of acquired immunodeficiency syndrome-related cancers. Optimizing highly active antiretroviral therapy and monitoring noncompliant patients with persisting HIV replication should be considered by physicians who take care of these patients. We herein report 2 cases of relapsed/progressive Burkitt lymphoma in HIV vertically infected adolescents.