Cortical Lamina and Fibrin Sealant for Horizontal Bone Augmentation Around Dental Implants: Proof-of-Principle With Histological Results.

This case report aimed to describe the medium-term results of the cortical lamina and fibrin sealant for horizontal bone augmentation at implant sites. A 62-year-old female American Society of Anesthesiologists I patient was treated with guided implant placement in the #3-#5 area. A mixture of collagenated xenogenic bone granules (OsteoBiol Gen-Os and OsteoBiol Apatos, Tecnoss, Giaveno, Italy) and fibrin sealant (Tisseel, Baxter Healthcare Corporation, Deerfield, IL) was carefully positioned in a single block with slight pressure on the recipient area. The xenogenic collagenated cortical lamina (OsteoBiol Lamina, Tecnoss) was shaped and placed over the augmented area. Fibrin sealant was also applied over the bone grafts to improve the lamina adhesion. After 5 months, a biopsy sample from the augmented area was harvested. The histological analysis showed newly formed bone in proximity to collagenated granules without a clear distinction. Signs of bone maturation were also noted. The 3D superimposition of the cone-beam computerized tomography scans showed that the bone volume at augmented sites remained stable during the 5-month healing period. Final prostheses were delivered 6 months after the second stage surgery with positive esthetic and functional results. The proposed technique demonstrated favorable outcomes in bone augmentation and stability.