Effect of rosmarinic acid on microtensile bond strength of 1-step self-etch adhesive on artificial caries-affected dentine with or without NaOCl treatment: An in-vitro study.

This study investigated the effect of rosmarinic acid (RA) on the immediate microtensile bond strength (µTBS) of 1-step self-etch adhesive to artificial caries-affected dentine (CAD), with or without NaOCl treatment. Dentine surfaces of 60 premolars were subjected to pH-cycling for artificial caries induction. Samples were randomly categorized into: NaOClRA group treated with 6% NaOCl and RA, RA group treated with RA solution, NaOCl group treated with 6% NaOCl, and untreated control group. Surface morphology was evaluated using SEM. Following bonding and composite placement, the specimens were sectioned into 1 mm2 beams after 24 h of water storage, then µTBS test was done. Failure modes were assessed under stereomicroscope. There was significant increase in the µTBS of NaOClRA compared to NaOCl group (p=0.001). RA group showed significant increase in µTBS compared to NaOCl and control groups, (p<0.001, p=0.009 respectively). In conclusion, RA improved the µTBS to CAD with or without NaOCl treatment.