British journal of urology · 1997
Potentially useful materials for biodegradable ureteric stents.
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Schlick R W, Planz K
Аннотация
OBJECTIVES: To develop and test materials that may be useful in the design and further development of biodegradable ureteric stents.
MATERIALS AND METHODS: Specimens of two plastics were placed in artificial urine of different pH for 30 days to examine the degree of dissolution of the plastic in alkaline and the stability in acidic conditions.
RESULTS: The specimens remained stable in the artificial urine at pH < 7.0 for 30 days and dissolved completely at a pH > or = 7 within 48 h.
CONCLUSION: Plastics can be designed which may be useful in the further development of biodegradable ureteric stents. The rate of dissolution could be changed by influencing urinary pH.
MATERIALS AND METHODS: Specimens of two plastics were placed in artificial urine of different pH for 30 days to examine the degree of dissolution of the plastic in alkaline and the stability in acidic conditions.
RESULTS: The specimens remained stable in the artificial urine at pH < 7.0 for 30 days and dissolved completely at a pH > or = 7 within 48 h.
CONCLUSION: Plastics can be designed which may be useful in the further development of biodegradable ureteric stents. The rate of dissolution could be changed by influencing urinary pH.