Anticancer research · 2016
Adenocarcinoma of the Oesophagus and Oesophagogastric Junction: Analysis of Incidence and Risk Factors.
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Rantanen Tuomo, Oksala Niku, Sand Juhani
Аннотация
BACKGROUND/AIM: Conflicting data exist on the changes in the incidence of oesophageal (EAC) and oesophagogastric junction adenocarcinoma (EGJAC). In addition, risk factors of the disease are only partly known. The aim of the study was to evaluate the incidence of EAC and EGJAC in Finland as well as risk factors of these cancers.
PATIENTS AND METHODS: The complete number of new EAC and EGJAC cases between January 1980 and December 2007 in Finland was provided by the Finnish Cancer Registry. All treated EAC and EGJAC patients in the Pirkanmaa Hospital District between January 1980 and December 2007 were included in the study.
RESULTS: The incidence of EAC increased significantly in Finland. Barrett's oesophagus (BE) was associated with the risk of EAC and cholecystectomy with the risk of EGJAC.
CONCLUSION: A significant increase in EAC was found in Finland over the course of nearly 30 years, indicating that the increase in EAC in Finland is existent in the long term. BE was associated with the risk of EAC and cholecystectomy with the risk of EGJAC.
PATIENTS AND METHODS: The complete number of new EAC and EGJAC cases between January 1980 and December 2007 in Finland was provided by the Finnish Cancer Registry. All treated EAC and EGJAC patients in the Pirkanmaa Hospital District between January 1980 and December 2007 were included in the study.
RESULTS: The incidence of EAC increased significantly in Finland. Barrett's oesophagus (BE) was associated with the risk of EAC and cholecystectomy with the risk of EGJAC.
CONCLUSION: A significant increase in EAC was found in Finland over the course of nearly 30 years, indicating that the increase in EAC in Finland is existent in the long term. BE was associated with the risk of EAC and cholecystectomy with the risk of EGJAC.
Предметные рубрики MeSH
AdenocarcinomaAdultAgedAged, 80 and overAlcohol DrinkingBarrett EsophagusCholecystectomyEsophageal NeoplasmsEsophagogastric JunctionFemaleFinlandFollow-Up StudiesFundoplicationGastroesophageal RefluxHumansIncidenceMaleMiddle AgedMorbidityNeoplasm StagingNeoplasms, Second PrimaryPrecancerous ConditionsRisk FactorsSex DistributionSmokingYoung Adult